The FDA has repeatedly stated that kratom is dangerous, saying it can lead addiction and in some cases, death. However, some experts continue to press forward to convince the Drug Enforcement Administration to legalize kratom — touted as an alternative approach to pain management.
http://admissions.iuhs.edu/?page_id=what-viagra-does write phd research proposal for phd admission follow site thesis umn https://www.go-gba.org/17651-perssuasive-essay/ http://jeromechamber.com/event/success-essay/23/ watch movie reveiws http://www.trinitypr.edu/admission/help-with-starting-a-research-paper/53/ engineering thesis essay for school uniforms https://nyusternldp.blogs.stern.nyu.edu/college-admission-essay-harvard/ click essays for cheap dissertation papers for sale robinson persuasive essay source site apa format proposal example resume layouts for free https://web.ics.purdue.edu/~asub/?doc=example-lab-report-biology click here how do i write my career objective for experience dissertation network https://thedsd.com/how-to-write-an-interview-essay/ see http://admissions.iuhs.edu/?page_id=nolvadex-pct-uk how to write joy in japanese how to write a letter for someone for university kmutt thesis format essay on white privilege trailers reviews viagra stores in jaipur Marc T. Swogger, PhD, a co-author of a 2018 article about kratom’s risks and benefits, told Healio Primary Care that there is “no good evidence that kratom is ‘deadly.’”
“The overall data suggest that kratom is a relatively mild plant that is helping people and is an important tool for fighting the opioid problem,” he said.
Those in favor of legalizing kratom say they have new evidence to make their point: a report in Preventive Medicine showing that the risk for overdose death is more than 1,000 times greater for opioid users than for kratom users.
“Our estimated range is based on import and export data from the American Kratom Association and the number of deaths that the FDA has associated with kratom to date,” Jack E. Henningfield, PhD, adjunct professor at Johns Hopkins University and lead author of the new report, said in an interview. “After that, it’s simple math.”
However, experts are questioning the accuracy of the findings.
For example, Bruce Chabner, MD, clinical director emeritus at Massachusetts General Hospital Cancer Center, said the estimate “depends on very soft data, such as whether clinicians accurately record all the drugs that the patients were taking.”
“Do clinicians ask a patient if they took kratom? In most instances, the answer is no,” he explained.
C. Michael White, PharmD, FCP, FCCP, head of the department of pharmacy practice at the University of Connecticut, agreed that the problem stems from the way data are collected on overdoses from kratom vs. opioids.
“You have apples and gorillas based on how the data are collected, and you are trying to do an apples-to-apples comparison,” he told Healio Primary Care.
White also said that kratom-attributed deaths are difficult to estimate in the face of polypharmacy.
“Until recently, no one looked for kratom, and it wasn’t a part of standard drug screens,” he said. In addition, “determining potential users by how much product is shipped to the United States is also quite imprecise. None of this means that Henningfield used an inferior method, just a poor one.”
Original Story By https://www.healio.com/primary-care/addiction/news/online/%7Bed3f111e-1933-4e7f-988c-b639d9027208%7D/kratoms-risk-obscured-by-soft-data